The Role of Kisspeptin in the Control of the Hypothalamic-Pituitary-Gonadal Axis and Reproduction
The discovery of kisspeptin as a critical central regulatory factor of GnRH release has given people a novel understanding of the neuroendocrine regulation in human reproduction.Kisspeptin activates the signaling pathway by binding to its receptor san jose sharks trucker hat kisspeptin receptor (KISS1R) to promote GnRH secretion, thereby regulating